Aluminium in PDB 9ltp: Crystal Structure of Human RAB43 in Gdp-ALF3 Transition State Complex with USP6NL Tbc Domain

The structure of Crystal Structure of Human RAB43 in Gdp-ALF3 Transition State Complex with USP6NL Tbc Domain, PDB code: 9ltp was solved by J.Wang, W.P.Yan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.99 / 2.49
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	50.669, 65.483, 98.76, 89.4, 76.73, 67.36
R / Rfree (%)	23.9 / 29.8

The structure of Crystal Structure of Human RAB43 in Gdp-ALF3 Transition State Complex with USP6NL Tbc Domain also contains other interesting chemical elements:

Fluorine	(F)	6 atoms
Magnesium	(Mg)	2 atoms

The binding sites of Aluminium atom in the Crystal Structure of Human RAB43 in Gdp-ALF3 Transition State Complex with USP6NL Tbc Domain (pdb code 9ltp). This binding sites where shown within 5.0 Angstroms radius around Aluminium atom.
In total 2 binding sites of Aluminium where determined in the Crystal Structure of Human RAB43 in Gdp-ALF3 Transition State Complex with USP6NL Tbc Domain, PDB code: 9ltp:
Jump to Aluminium binding site number: 1; 2;

Aluminium binding site 1 out of 2 in the Crystal Structure of Human RAB43 in Gdp-ALF3 Transition State Complex with USP6NL Tbc Domain


Mono view


Stereo pair view

A full contact list of Aluminium with other atoms in the Al binding site number 1 of Crystal Structure of Human RAB43 in Gdp-ALF3 Transition State Complex with USP6NL Tbc Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Al203 b:47.6 occ:1.00 AL B:AF3203 0.0 47.6 1.0 F1 B:AF3203 1.6 30.3 1.0 F2 B:AF3203 1.6 20.9 1.0 F3 B:AF3203 1.6 26.0 1.0 O3B B:GDP202 2.5 28.6 1.0 MG B:MG201 3.4 12.2 1.0 PB B:GDP202 3.5 13.6 1.0 O1B B:GDP202 3.7 16.7 1.0 N B:GLY76 3.8 17.6 1.0 NE2 A:GLN187 3.8 11.7 1.0 O2B B:GDP202 3.9 22.7 1.0 NH1 A:ARG150 3.9 19.4 1.0 N B:THR50 4.0 23.0 1.0 OE1 A:GLN187 4.2 16.9 1.0 O B:HOH307 4.2 12.3 1.0 CB B:THR50 4.3 15.6 1.0 NZ B:LYS31 4.4 13.8 1.0 N B:SER28 4.4 16.7 1.0 CA B:ALA75 4.4 27.8 1.0 CD A:GLN187 4.5 11.7 1.0 NH2 A:ARG150 4.5 12.2 1.0 CA B:ALA27 4.5 15.7 1.0 O B:THR50 4.5 25.0 1.0 CA B:GLY76 4.5 11.8 1.0 O B:THR74 4.5 16.6 1.0 C B:ALA75 4.6 28.3 1.0 CB B:ALA27 4.6 13.8 1.0 OG1 B:THR50 4.6 12.0 1.0 CZ A:ARG150 4.6 14.2 1.0 CA B:THR50 4.7 22.6 1.0 CA B:SER49 4.9 18.4 1.0 O2A B:GDP202 4.9 17.7 1.0 CB B:SER49 4.9 24.5 1.0 O3A B:GDP202 4.9 18.0 1.0 C B:SER49 5.0 11.8 1.0 C B:ALA27 5.0 15.0 1.0

Aluminium binding site 2 out of 2 in the Crystal Structure of Human RAB43 in Gdp-ALF3 Transition State Complex with USP6NL Tbc Domain


Mono view


Stereo pair view

A full contact list of Aluminium with other atoms in the Al binding site number 2 of Crystal Structure of Human RAB43 in Gdp-ALF3 Transition State Complex with USP6NL Tbc Domain within 5.0Å range: probe atom residue distance (Å) B Occ D:Al203 b:33.8 occ:1.00 AL D:AF3203 0.0 33.8 1.0 F3 D:AF3203 1.6 29.1 1.0 F1 D:AF3203 1.6 25.5 1.0 F2 D:AF3203 1.6 33.9 1.0 O2B D:GDP202 2.5 19.8 1.0 NE2 C:GLN187 3.3 11.8 1.0 MG D:MG201 3.5 16.2 1.0 NH1 C:ARG150 3.7 13.2 1.0 PB D:GDP202 3.8 25.1 1.0 NH2 C:ARG150 3.9 12.3 1.0 OE1 C:GLN187 3.9 17.6 1.0 N D:GLY76 4.0 25.3 1.0 CD C:GLN187 4.0 13.8 1.0 O1B D:GDP202 4.1 12.6 1.0 N D:THR50 4.1 11.5 1.0 N D:SER28 4.1 16.2 1.0 O D:HOH302 4.1 20.8 1.0 CA D:ALA27 4.2 16.6 1.0 CZ C:ARG150 4.2 15.2 1.0 CB D:ALA27 4.3 16.6 1.0 O D:THR50 4.4 19.8 1.0 CA D:ALA75 4.4 34.9 1.0 NZ D:LYS31 4.5 12.8 1.0 O3A D:GDP202 4.5 19.3 1.0 CB D:THR50 4.6 20.4 1.0 CB D:SER49 4.7 15.6 1.0 CA D:SER49 4.7 21.2 1.0 C D:ALA75 4.7 28.9 1.0 C D:ALA27 4.7 24.4 1.0 CA D:GLY76 4.8 20.8 1.0 CB D:ALA75 4.8 33.0 1.0 C D:SER49 4.8 11.4 1.0 CA D:THR50 4.8 20.6 1.0 OG1 D:THR50 4.9 33.8 1.0 O3B D:GDP202 4.9 16.9 1.0 O D:THR74 5.0 17.1 1.0

J.Wang, T.Liu, Z.Zhang, W.Yan. Molecular Basis of RAB43 Inactivation By Rn-Tre in Endocytic Trafficking Unveils A General Rab-Gap Recognition Mechanism. Int.J.Biol.Macromol. V. 338 49561 2025.
ISSN: ISSN 0141-8130
PubMed: 41401861
DOI: 10.1016/J.IJBIOMAC.2025.149561