Aluminium in PDB 1fqk: Crystal Structure of the Heterodimeric Complex of the Rgs Domain of RGS9, and the Gt/I1 Chimera Alpha Subunit [(RGS9)-(Gt/I1ALPHA)-(Gdp)- (ALF4-)-(MG2+)]

The structure of Crystal Structure of the Heterodimeric Complex of the Rgs Domain of RGS9, and the Gt/I1 Chimera Alpha Subunit [(RGS9)-(Gt/I1ALPHA)-(Gdp)- (ALF4-)-(MG2+)], PDB code: 1fqk was solved by K.C.Slep, M.A.Kercher, W.He, C.W.Cowan, T.G.Wensel, P.B.Sigler, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.30
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	96.785, 115.073, 136.460, 90.00, 90.00, 90.00
R / Rfree (%)	23.1 / 26.8

The structure of Crystal Structure of the Heterodimeric Complex of the Rgs Domain of RGS9, and the Gt/I1 Chimera Alpha Subunit [(RGS9)-(Gt/I1ALPHA)-(Gdp)- (ALF4-)-(MG2+)] also contains other interesting chemical elements:

Fluorine	(F)	8 atoms
Magnesium	(Mg)	2 atoms

The binding sites of Aluminium atom in the Crystal Structure of the Heterodimeric Complex of the Rgs Domain of RGS9, and the Gt/I1 Chimera Alpha Subunit [(RGS9)-(Gt/I1ALPHA)-(Gdp)- (ALF4-)-(MG2+)] (pdb code 1fqk). This binding sites where shown within 5.0 Angstroms radius around Aluminium atom.
In total 2 binding sites of Aluminium where determined in the Crystal Structure of the Heterodimeric Complex of the Rgs Domain of RGS9, and the Gt/I1 Chimera Alpha Subunit [(RGS9)-(Gt/I1ALPHA)-(Gdp)- (ALF4-)-(MG2+)], PDB code: 1fqk:
Jump to Aluminium binding site number: 1; 2;

Aluminium binding site 1 out of 2 in the Crystal Structure of the Heterodimeric Complex of the Rgs Domain of RGS9, and the Gt/I1 Chimera Alpha Subunit [(RGS9)-(Gt/I1ALPHA)-(Gdp)- (ALF4-)-(MG2+)]


Mono view


Stereo pair view

A full contact list of Aluminium with other atoms in the Al binding site number 1 of Crystal Structure of the Heterodimeric Complex of the Rgs Domain of RGS9, and the Gt/I1 Chimera Alpha Subunit [(RGS9)-(Gt/I1ALPHA)-(Gdp)- (ALF4-)-(MG2+)] within 5.0Å range: probe atom residue distance (Å) B Occ A:Al362 b:51.9 occ:1.00 AL A:ALF362 0.0 51.9 1.0 F1 A:ALF362 1.7 55.0 1.0 F4 A:ALF362 1.8 50.2 1.0 F2 A:ALF362 1.8 55.2 1.0 F3 A:ALF362 1.8 49.8 1.0 O A:HOH363 2.2 56.8 1.0 O3B A:GDP360 2.7 57.0 1.0 O2B A:GDP360 3.3 53.9 1.0 PB A:GDP360 3.5 56.3 1.0 MG A:MG352 3.7 47.9 1.0 N A:GLU39 3.8 39.8 1.0 OG1 A:THR177 3.8 58.8 1.0 NH1 A:ARG174 3.8 45.0 1.0 NZ A:LYS42 3.9 50.0 1.0 NH2 A:ARG174 4.0 42.7 1.0 N A:GLY199 4.0 52.6 1.0 O A:HOH365 4.1 49.8 1.0 O A:HOH364 4.1 44.7 1.0 OE1 A:GLN200 4.2 55.4 1.0 N A:THR177 4.3 49.1 1.0 CA A:GLY38 4.3 43.6 1.0 NE2 A:GLN200 4.3 45.9 1.0 O1B A:GDP360 4.4 60.8 1.0 CZ A:ARG174 4.4 42.4 1.0 O3A A:GDP360 4.5 54.3 1.0 O A:THR177 4.6 50.4 1.0 C A:GLY38 4.6 44.5 1.0 CE A:LYS42 4.7 44.6 1.0 CD A:GLN200 4.7 51.4 1.0 CA A:GLU39 4.7 42.2 1.0 CA A:GLY199 4.8 49.9 1.0 CA A:GLY198 4.8 54.2 1.0 CG A:LYS176 4.8 42.8 1.0 O2A A:GDP360 4.8 52.0 1.0 C A:GLY198 4.9 53.5 1.0 CA A:LYS176 4.9 45.8 1.0 CB A:THR177 5.0 57.3 1.0

Aluminium binding site 2 out of 2 in the Crystal Structure of the Heterodimeric Complex of the Rgs Domain of RGS9, and the Gt/I1 Chimera Alpha Subunit [(RGS9)-(Gt/I1ALPHA)-(Gdp)- (ALF4-)-(MG2+)]


Mono view


Stereo pair view

A full contact list of Aluminium with other atoms in the Al binding site number 2 of Crystal Structure of the Heterodimeric Complex of the Rgs Domain of RGS9, and the Gt/I1 Chimera Alpha Subunit [(RGS9)-(Gt/I1ALPHA)-(Gdp)- (ALF4-)-(MG2+)] within 5.0Å range: probe atom residue distance (Å) B Occ C:Al363 b:52.5 occ:1.00 AL C:ALF363 0.0 52.5 1.0 F4 C:ALF363 1.7 55.4 1.0 F1 C:ALF363 1.7 52.2 1.0 F2 C:ALF363 1.8 53.3 1.0 F3 C:ALF363 1.8 44.4 1.0 O C:HOH364 2.0 49.8 1.0 O3B C:GDP361 2.8 66.0 1.0 O2B C:GDP361 3.3 55.7 1.0 PB C:GDP361 3.5 61.0 1.0 NH1 C:ARG174 3.8 40.9 1.0 MG C:MG352 3.9 58.0 1.0 N C:GLU39 3.9 46.2 1.0 O C:HOH365 3.9 40.8 1.0 N C:THR177 4.0 44.6 1.0 O C:HOH366 4.0 45.5 1.0 NH2 C:ARG174 4.1 41.6 1.0 N C:GLY199 4.1 42.4 1.0 OE1 C:GLN200 4.1 46.2 1.0 NZ C:LYS42 4.2 41.1 1.0 NE2 C:GLN200 4.2 45.6 1.0 CA C:GLY38 4.3 44.2 1.0 CZ C:ARG174 4.4 47.7 1.0 OG1 C:THR177 4.4 49.8 1.0 CB C:THR177 4.4 46.6 1.0 O C:THR177 4.6 47.7 1.0 O1B C:GDP361 4.6 67.2 1.0 O3A C:GDP361 4.6 58.3 1.0 CG C:LYS176 4.6 41.5 1.0 CD C:GLN200 4.6 43.8 1.0 C C:GLY38 4.7 49.7 1.0 CA C:LYS176 4.7 47.5 1.0 CE C:LYS42 4.7 41.6 1.0 CA C:THR177 4.7 45.2 1.0 CA C:GLU39 4.8 45.7 1.0 CA C:GLY198 4.8 44.9 1.0 O2A C:GDP361 4.8 56.7 1.0 C C:LYS176 4.9 49.1 1.0 CA C:GLY199 4.9 44.3 1.0 C C:GLY198 4.9 40.4 1.0

K.C.Slep, M.A.Kercher, W.He, C.W.Cowan, T.G.Wensel, P.B.Sigler. Structural Determinants For Regulation of Phosphodiesterase By A G Protein at 2.0 A. Nature V. 409 1071 2001.
ISSN: ISSN 0028-0836
PubMed: 11234020
DOI: 10.1038/35059138