Aluminium in PDB 1zca: Crystal Structure of G Alpha 12 in Complex with Gdp, MG2+ and ALF4-

The structure of Crystal Structure of G Alpha 12 in Complex with Gdp, MG2+ and ALF4-, PDB code: 1zca was solved by M.R.Nance, J.J.G.Tesmer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.10 / 2.90
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	57.501, 85.230, 82.885, 90.00, 106.09, 90.00
R / Rfree (%)	23.6 / 29.6

The structure of Crystal Structure of G Alpha 12 in Complex with Gdp, MG2+ and ALF4- also contains other interesting chemical elements:

Fluorine	(F)	8 atoms
Magnesium	(Mg)	2 atoms

The binding sites of Aluminium atom in the Crystal Structure of G Alpha 12 in Complex with Gdp, MG2+ and ALF4- (pdb code 1zca). This binding sites where shown within 5.0 Angstroms radius around Aluminium atom.
In total 2 binding sites of Aluminium where determined in the Crystal Structure of G Alpha 12 in Complex with Gdp, MG2+ and ALF4-, PDB code: 1zca:
Jump to Aluminium binding site number: 1; 2;

Aluminium binding site 1 out of 2 in the Crystal Structure of G Alpha 12 in Complex with Gdp, MG2+ and ALF4-


Mono view


Stereo pair view

A full contact list of Aluminium with other atoms in the Al binding site number 1 of Crystal Structure of G Alpha 12 in Complex with Gdp, MG2+ and ALF4- within 5.0Å range: probe atom residue distance (Å) B Occ A:Al384 b:34.1 occ:1.00 AL A:ALF384 0.0 34.1 1.0 F4 A:ALF384 1.8 33.5 1.0 F3 A:ALF384 1.8 33.7 1.0 F2 A:ALF384 1.8 34.2 1.0 F1 A:ALF384 1.8 33.5 1.0 O3B A:GDP382 2.0 17.2 1.0 O A:HOH385 2.2 35.5 1.0 MG A:MG383 3.1 22.7 1.0 PB A:GDP382 3.2 16.9 1.0 O2B A:GDP382 3.5 19.1 1.0 O A:HOH386 3.8 13.7 1.0 NH1 A:ARG203 3.9 20.5 1.0 N A:GLY228 3.9 35.6 1.0 OE1 A:GLN229 3.9 38.7 1.0 N A:THR206 4.0 31.0 1.0 O A:HOH387 4.0 53.8 1.0 O1B A:GDP382 4.0 15.9 1.0 N A:GLU65 4.2 33.7 1.0 CA A:GLY227 4.3 36.6 1.0 OG1 A:THR206 4.3 32.4 1.0 CE A:LYS68 4.4 26.0 1.0 CB A:THR206 4.4 31.8 1.0 NH2 A:ARG203 4.4 20.9 1.0 O3A A:GDP382 4.4 19.6 1.0 NZ A:LYS68 4.5 25.1 1.0 CA A:GLY64 4.5 33.0 1.0 CZ A:ARG203 4.5 20.4 1.0 O A:THR206 4.6 32.4 1.0 C A:GLY227 4.7 35.7 1.0 CD A:GLN229 4.7 37.4 1.0 CA A:THR206 4.7 31.8 1.0 NE2 A:GLN229 4.7 37.3 1.0 CA A:GLY228 4.8 36.0 1.0 CA A:ALA205 4.8 29.2 1.0 C A:GLY64 4.9 33.5 1.0 C A:ALA205 4.9 29.9 1.0 O2A A:GDP382 4.9 19.9 1.0

Aluminium binding site 2 out of 2 in the Crystal Structure of G Alpha 12 in Complex with Gdp, MG2+ and ALF4-


Mono view


Stereo pair view

A full contact list of Aluminium with other atoms in the Al binding site number 2 of Crystal Structure of G Alpha 12 in Complex with Gdp, MG2+ and ALF4- within 5.0Å range: probe atom residue distance (Å) B Occ B:Al1384 b:44.5 occ:1.00 AL B:ALF1384 0.0 44.5 1.0 F4 B:ALF1384 1.8 45.1 1.0 F2 B:ALF1384 1.8 45.2 1.0 F3 B:ALF1384 1.8 45.5 1.0 F1 B:ALF1384 1.8 44.6 1.0 O3B B:GDP1382 2.0 27.9 1.0 O B:HOH1385 2.1 18.3 1.0 MG B:MG1383 2.7 27.2 1.0 PB B:GDP1382 3.3 27.2 1.0 O2B B:GDP1382 3.8 26.9 1.0 N B:GLY228 3.8 39.0 1.0 OE1 B:GLN229 3.8 41.1 1.0 O B:HOH1386 3.9 18.1 1.0 O1B B:GDP1382 3.9 28.1 1.0 NH1 B:ARG203 3.9 26.8 1.0 O B:HOH1387 4.0 60.1 1.0 N B:THR206 4.0 34.3 1.0 N B:GLU65 4.2 34.2 1.0 CA B:GLY227 4.3 40.1 1.0 NH2 B:ARG203 4.3 27.5 1.0 CE B:LYS68 4.3 28.2 1.0 NE2 B:GLN229 4.3 39.1 1.0 NZ B:LYS68 4.4 28.9 1.0 CA B:GLY64 4.4 33.8 1.0 CD B:GLN229 4.4 40.0 1.0 CB B:THR206 4.5 34.6 1.0 CZ B:ARG203 4.5 27.6 1.0 O3A B:GDP1382 4.5 27.1 1.0 C B:GLY227 4.6 39.5 1.0 O B:THR206 4.6 35.7 1.0 OG1 B:THR206 4.6 34.3 1.0 CA B:GLY228 4.7 39.0 1.0 CA B:THR206 4.7 34.9 1.0 CA B:ALA205 4.9 33.0 1.0 C B:GLY64 4.9 34.1 1.0 C B:ALA205 4.9 33.7 1.0

B.Kreutz, D.M.Yau, M.R.Nance, S.Tanabe, J.J.Tesmer, T.Kozasa. A New Approach to Producing Functional G Alpha Subunits Yields the Activated and Deactivated Structures of G Alpha(12/13) Proteins. Biochemistry V. 45 167 2006.
ISSN: ISSN 0006-2960
PubMed: 16388592
DOI: 10.1021/BI051729T