Aluminium in PDB 2g83: Structure of Activated G-Alpha-I1 Bound to A Nucleotide- State-Selective Peptide: Minimal Determinants For Recognizing the Active Form of A G Protein Alpha Subunit

The structure of Structure of Activated G-Alpha-I1 Bound to A Nucleotide- State-Selective Peptide: Minimal Determinants For Recognizing the Active Form of A G Protein Alpha Subunit, PDB code: 2g83 was solved by C.A.Johnston, J.K.Ramer, R.Blaesius, B.Kuhlman, V.Y.Arshavsky, D.P.Siderovski, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.80
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	103.130, 103.130, 206.990, 90.00, 90.00, 120.00
R / Rfree (%)	26.9 / 30

The structure of Structure of Activated G-Alpha-I1 Bound to A Nucleotide- State-Selective Peptide: Minimal Determinants For Recognizing the Active Form of A G Protein Alpha Subunit also contains other interesting chemical elements:

Fluorine	(F)	8 atoms
Magnesium	(Mg)	2 atoms

The binding sites of Aluminium atom in the Structure of Activated G-Alpha-I1 Bound to A Nucleotide- State-Selective Peptide: Minimal Determinants For Recognizing the Active Form of A G Protein Alpha Subunit (pdb code 2g83). This binding sites where shown within 5.0 Angstroms radius around Aluminium atom.
In total 2 binding sites of Aluminium where determined in the Structure of Activated G-Alpha-I1 Bound to A Nucleotide- State-Selective Peptide: Minimal Determinants For Recognizing the Active Form of A G Protein Alpha Subunit, PDB code: 2g83:
Jump to Aluminium binding site number: 1; 2;

Aluminium binding site 1 out of 2 in the Structure of Activated G-Alpha-I1 Bound to A Nucleotide- State-Selective Peptide: Minimal Determinants For Recognizing the Active Form of A G Protein Alpha Subunit


Mono view


Stereo pair view

A full contact list of Aluminium with other atoms in the Al binding site number 1 of Structure of Activated G-Alpha-I1 Bound to A Nucleotide- State-Selective Peptide: Minimal Determinants For Recognizing the Active Form of A G Protein Alpha Subunit within 5.0Å range: probe atom residue distance (Å) B Occ A:Al357 b:56.2 occ:1.00 AL A:ALF357 0.0 56.2 1.0 F1 A:ALF357 1.7 55.6 1.0 F4 A:ALF357 1.7 54.9 1.0 F2 A:ALF357 1.7 53.6 1.0 F3 A:ALF357 1.7 53.9 1.0 O1B A:GDP355 3.4 39.6 1.0 OE1 A:GLN204 3.5 51.8 1.0 O3B A:GDP355 3.6 34.7 1.0 NH2 A:ARG178 3.7 34.9 1.0 NH1 A:ARG178 3.7 37.5 1.0 NE2 A:GLN204 3.8 50.2 1.0 MG A:MG356 3.8 29.3 1.0 N A:THR181 3.8 37.6 1.0 OG1 A:THR181 3.9 42.1 1.0 PB A:GDP355 3.9 39.4 1.0 O A:THR181 3.9 41.9 1.0 N A:GLY203 3.9 61.1 1.0 CD A:GLN204 4.0 50.5 1.0 CG A:LYS180 4.1 36.0 1.0 CZ A:ARG178 4.2 36.9 1.0 CB A:THR181 4.2 42.6 1.0 N A:GLU43 4.2 41.0 1.0 CA A:GLY202 4.2 37.7 1.0 O2B A:GDP355 4.2 37.6 1.0 CA A:GLY42 4.5 37.9 1.0 CA A:THR181 4.5 37.7 1.0 CA A:LYS180 4.6 30.3 1.0 C A:GLY202 4.6 39.7 1.0 NZ A:LYS46 4.6 43.6 1.0 C A:THR181 4.7 39.7 1.0 C A:LYS180 4.7 30.5 1.0 O A:HOH2 4.8 44.1 1.0 C A:GLY42 4.9 38.6 1.0 CB A:LYS180 4.9 35.1 1.0 CA A:GLY203 4.9 63.1 1.0 O A:VAL201 5.0 30.8 1.0

Aluminium binding site 2 out of 2 in the Structure of Activated G-Alpha-I1 Bound to A Nucleotide- State-Selective Peptide: Minimal Determinants For Recognizing the Active Form of A G Protein Alpha Subunit


Mono view


Stereo pair view

A full contact list of Aluminium with other atoms in the Al binding site number 2 of Structure of Activated G-Alpha-I1 Bound to A Nucleotide- State-Selective Peptide: Minimal Determinants For Recognizing the Active Form of A G Protein Alpha Subunit within 5.0Å range: probe atom residue distance (Å) B Occ B:Al359 b:61.6 occ:1.00 AL B:ALF359 0.0 61.6 1.0 F2 B:ALF359 1.7 59.9 1.0 F3 B:ALF359 1.7 63.7 1.0 F1 B:ALF359 1.7 62.9 1.0 F4 B:ALF359 1.7 65.1 1.0 O1B B:GDP355 2.0 44.3 1.0 MG B:MG358 3.3 45.1 1.0 PB B:GDP355 3.5 42.4 1.0 NH2 B:ARG178 3.5 55.4 1.0 OE1 B:GLN204 3.5 38.2 1.0 N B:THR181 3.7 46.8 1.0 OG1 B:THR181 3.7 41.8 1.0 NH1 B:ARG178 3.8 54.3 1.0 O3B B:GDP355 3.9 39.1 1.0 CB B:THR181 4.0 41.7 1.0 NE2 B:GLN204 4.1 38.5 1.0 CZ B:ARG178 4.1 54.5 1.0 O B:THR181 4.2 45.1 1.0 N B:GLY203 4.2 63.0 1.0 CD B:GLN204 4.2 39.5 1.0 N B:GLU43 4.2 49.3 1.0 O2B B:GDP355 4.3 38.5 1.0 CG B:LYS180 4.3 51.7 1.0 CA B:GLY202 4.4 33.9 1.0 CA B:THR181 4.4 44.8 1.0 O B:HOH1 4.4 35.6 1.0 CA B:LYS180 4.4 47.2 1.0 O3A B:GDP355 4.6 45.5 1.0 C B:LYS180 4.6 46.6 1.0 CA B:GLY42 4.7 65.0 1.0 C B:THR181 4.8 45.0 1.0 OG B:SER47 4.8 41.2 1.0 C B:GLY202 4.8 35.4 1.0 CB B:LYS180 4.9 50.3 1.0 C B:GLY42 5.0 65.0 1.0 CA B:GLU43 5.0 47.9 1.0 NZ B:LYS46 5.0 48.5 1.0

C.A.Johnston, E.S.Lobanova, A.S.Shavkunov, J.Low, J.K.Ramer, R.Blaesius, Z.Fredericks, F.S.Willard, B.Kuhlman, V.Y.Arshavsky, D.P.Siderovski. Minimal Determinants For Binding Activated Galpha From the Structure of A Galpha(I1)-Peptide Dimer. Biochemistry V. 45 11390 2006.
ISSN: ISSN 0006-2960
PubMed: 16981699
DOI: 10.1021/BI0613832