Aluminium in PDB 2xzl: UPF1-Rna Complex

All present enzymatic activity of UPF1-Rna Complex:
3.6.4.13;

The structure of UPF1-Rna Complex, PDB code: 2xzl was solved by S.Chakrabarti, U.Jayachandran, F.Bonneau, F.Fiorini, C.Basquin, S.Domcke, H.Le Hir, E.Conti, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.882 / 2.40
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	64.135, 114.117, 65.730, 90.00, 110.24, 90.00
R / Rfree (%)	19.74 / 24.31

The structure of UPF1-Rna Complex also contains other interesting chemical elements:

Zinc	(Zn)	3 atoms
Magnesium	(Mg)	1 atom
Fluorine	(F)	4 atoms

The binding sites of Aluminium atom in the UPF1-Rna Complex (pdb code 2xzl). This binding sites where shown within 5.0 Angstroms radius around Aluminium atom.
In total only one binding site of Aluminium was determined in the UPF1-Rna Complex, PDB code: 2xzl:

Aluminium binding site 1 out of 1 in the UPF1-Rna Complex


Mono view


Stereo pair view

A full contact list of Aluminium with other atoms in the Al binding site number 1 of UPF1-Rna Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Al1855 b:8.6 occ:1.00 AL A:ALF1855 0.0 8.6 1.0 F4 A:ALF1855 1.8 9.5 1.0 F1 A:ALF1855 1.8 7.8 1.0 F3 A:ALF1855 1.8 10.3 1.0 F2 A:ALF1855 1.8 9.6 1.0 O1B A:ADP1854 2.2 8.6 1.0 O A:HOH2051 2.2 4.5 1.0 PB A:ADP1854 3.6 6.8 1.0 MG A:MG1856 3.8 12.6 1.0 NH2 A:ARG639 3.8 9.1 1.0 NH1 A:ARG801 3.9 6.7 1.0 NH2 A:ARG801 4.0 6.3 1.0 N A:GLY433 4.0 5.5 1.0 OE1 A:GLN601 4.0 7.6 1.0 O2B A:ADP1854 4.0 10.2 1.0 NH1 A:ARG639 4.0 5.8 1.0 NE2 A:GLN601 4.1 5.5 1.0 CA A:GLY767 4.1 8.3 1.0 NZ A:LYS436 4.2 6.7 1.0 CA A:PRO432 4.2 5.5 1.0 O3B A:ADP1854 4.3 9.9 1.0 N A:GLY767 4.3 8.4 1.0 O A:HOH2025 4.4 21.4 1.0 CZ A:ARG639 4.4 9.8 1.0 CZ A:ARG801 4.4 6.9 1.0 O A:HOH2090 4.5 5.5 1.0 CD A:GLN601 4.5 10.0 1.0 O A:HOH2073 4.5 20.9 1.0 O A:HOH2047 4.6 20.1 1.0 O3A A:ADP1854 4.6 14.8 1.0 CB A:PRO432 4.6 4.8 1.0 C A:PRO432 4.6 6.2 1.0 CE A:LYS436 4.8 8.3 1.0 C A:GLY767 4.9 10.1 1.0 CA A:GLY433 4.9 7.3 1.0

S.Chakrabarti, U.Jayachandran, F.Bonneau, F.Fiorini, C.Basquin, S.Domcke, H.Le Hir, E.Conti. Molecular Mechanisms For the Rna-Dependent Atpase Activity of UPF1 and Its Regulation By UPF2. Mol.Cell V. 41 693 2011.
ISSN: ISSN 1097-2765
PubMed: 21419344
DOI: 10.1016/J.MOLCEL.2011.02.010