Aluminium in the structure of Molecular Architecture of Galphao and the Structural Basis For RGS16-Mediated Deactivation (pdb 3c7k)

The binding sites of Aluminium atom in the structure of Molecular Architecture of Galphao and the Structural Basis For RGS16-Mediated Deactivation (pdb code 3c7k). This binding sites where shown with 5.0 Angstroms radius around Aluminium atom. The 3c7k structure was solved by K.C.SLEP, M.A.KERCHER, T.WIELAND, C.CHEN, M.I.SIMON, P.B.SIGLER, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 50.0-2.9 Space group P3221 a (A) 96.357 b (A) 96.357 c (A) 235.610 alpha (°) 90.00 beta (°) 90.00 gamma (°) 120.00 Rfactor (%) 25 Rfree (%) 31.1 Aluminium Binding Sites: Aluminium binding site 1 out of 2 in 3c7k Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Aluminium in the PDB 3c7k. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Aluminium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Gly42, A: Glu43, A: Lys46, A: Arg179, A: Lys181, A: Thr182, A: Val202, A: Gly203, A: Gly204, A: Gln205, A: Gdp361, A: Mg362, A: Alf365, A: Hoh401, A: Hoh402, A: Hoh403, conact list: Atom Atom Distance (A) Al C A:Gly42 4.74 Al CA A:Gly42 4.60 Al N A:Glu43 3.85 Al CA A:Glu43 4.58 Al CE A:Lys46 4.34 Al NZ A:Lys46 3.69 Al CZ A:Arg179 4.26 Al NH2 A:Arg179 4.01 Al NH1 A:Arg179 3.57 Al C A:Lys181 4.87 Al CG A:Lys181 4.72 Al CA A:Lys181 4.59 Al O A:Thr182 4.74 Al N A:Thr182 4.08 Al CB A:Thr182 4.63 Al OG1 A:Thr182 4.73 Al CA A:Thr182 4.90 Al O A:Val202 4.84 Al CA A:Gly203 4.97 Al N A:Gly204 4.07 Al CA A:Gly204 4.73 Al NE2 A:Gln205 3.95 Al OE1 A:Gln205 4.26 Al CD A:Gln205 4.56 Al O3B A:Gdp361 2.51 Al O2A A:Gdp361 5.00 Al O1B A:Gdp361 3.49 Al PB A:Gdp361 3.08 Al O2B A:Gdp361 3.20 Al O3A A:Gdp361 4.43 Al MG A:Mg362 3.28 Al F4 A:Alf365 1.80 Al F3 A:Alf365 1.79 Al F2 A:Alf365 1.80 Al AL A:Alf365 0.00 Al F1 A:Alf365 1.79 Al O A:Hoh401 2.07 Al O A:Hoh402 4.82 Al O A:Hoh403 4.57 interactive model: Aluminium binding site 2 out of 2 in 3c7k Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Aluminium in the PDB 3c7k. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Aluminium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: C: Gly42, C: Glu43, C: Lys46, C: Arg179, C: Lys181, C: Thr182, C: Val202, C: Gly204, C: Gln205, C: Gdp361, C: Mg362, C: Alf365, C: Hoh401, C: Hoh402, C: Hoh403, conact list: Atom Atom Distance (A) Al C C:Gly42 4.82 Al CA C:Gly42 4.82 Al N C:Glu43 4.01 Al CA C:Glu43 4.62 Al CE C:Lys46 4.48 Al NZ C:Lys46 3.62 Al CZ C:Arg179 4.35 Al NH2 C:Arg179 4.15 Al NH1 C:Arg179 3.64 Al C C:Lys181 4.81 Al CG C:Lys181 4.61 Al CA C:Lys181 4.60 Al O C:Thr182 4.45 Al N C:Thr182 3.95 Al CB C:Thr182 4.42 Al OG1 C:Thr182 4.92 Al CA C:Thr182 4.67 Al O C:Val202 4.92 Al N C:Gly204 4.12 Al CA C:Gly204 4.77 Al NE2 C:Gln205 4.54 Al OE1 C:Gln205 4.07 Al CD C:Gln205 4.75 Al O3B C:Gdp361 2.56 Al O2A C:Gdp361 4.96 Al O1B C:Gdp361 4.19 Al PB C:Gdp361 3.55 Al O2B C:Gdp361 3.59 Al O3A C:Gdp361 4.75 Al MG C:Mg362 3.69 Al F4 C:Alf365 1.71 Al F3 C:Alf365 1.84 Al F2 C:Alf365 1.76 Al AL C:Alf365 0.00 Al F1 C:Alf365 1.75 Al O C:Hoh401 2.25 Al O C:Hoh402 4.37 Al O C:Hoh403 4.56 interactive model: