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Aluminium in PDB 9f20: Cryo-Em Structure of the I923V MDA5-Dsrna Filament with Adp-ALF4 Bound and 88-Degree Helical Twist

Enzymatic activity of Cryo-Em Structure of the I923V MDA5-Dsrna Filament with Adp-ALF4 Bound and 88-Degree Helical Twist

All present enzymatic activity of Cryo-Em Structure of the I923V MDA5-Dsrna Filament with Adp-ALF4 Bound and 88-Degree Helical Twist:
3.6.4.13;

Other elements in 9f20:

The structure of Cryo-Em Structure of the I923V MDA5-Dsrna Filament with Adp-ALF4 Bound and 88-Degree Helical Twist also contains other interesting chemical elements:

Fluorine (F) 4 atoms
Zinc (Zn) 1 atom

Aluminium Binding Sites:

The binding sites of Aluminium atom in the Cryo-Em Structure of the I923V MDA5-Dsrna Filament with Adp-ALF4 Bound and 88-Degree Helical Twist (pdb code 9f20). This binding sites where shown within 5.0 Angstroms radius around Aluminium atom.
In total only one binding site of Aluminium was determined in the Cryo-Em Structure of the I923V MDA5-Dsrna Filament with Adp-ALF4 Bound and 88-Degree Helical Twist, PDB code: 9f20:

Aluminium binding site 1 out of 1 in 9f20

Go back to Aluminium Binding Sites List in 9f20
Aluminium binding site 1 out of 1 in the Cryo-Em Structure of the I923V MDA5-Dsrna Filament with Adp-ALF4 Bound and 88-Degree Helical Twist


Mono view


Stereo pair view

A full contact list of Aluminium with other atoms in the Al binding site number 1 of Cryo-Em Structure of the I923V MDA5-Dsrna Filament with Adp-ALF4 Bound and 88-Degree Helical Twist within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Al1102

b:178.1
occ:1.00
AL A:ALF1102 0.0 178.1 1.0
F3 A:ALF1102 1.8 178.1 1.0
F1 A:ALF1102 1.8 178.1 1.0
F4 A:ALF1102 1.8 178.1 1.0
F2 A:ALF1102 1.8 178.1 1.0
O2B A:ADP1101 2.1 151.1 1.0
PB A:ADP1101 3.0 151.1 1.0
O3B A:ADP1101 3.3 151.1 1.0
HG22 A:THR332 3.7 160.1 1.0
HZ2 A:LYS336 3.7 135.4 1.0
O1B A:ADP1101 3.7 151.1 1.0
OE1 A:GLU445 3.8 113.7 1.0
HD2 A:LYS336 3.9 135.4 1.0
HA A:THR332 4.2 160.1 1.0
HB3 A:ALA490 4.2 135.6 1.0
O3A A:ADP1101 4.4 151.1 1.0
HZ3 A:LYS336 4.4 135.4 1.0
OE2 A:GLU794 4.4 154.7 1.0
NZ A:LYS336 4.4 135.4 1.0
CG2 A:THR332 4.6 160.1 1.0
HB A:THR332 4.6 160.1 1.0
H A:GLY333 4.6 156.3 1.0
CD A:LYS336 4.8 135.4 1.0
CD A:GLU445 4.8 113.7 1.0
HG21 A:THR332 4.9 160.1 1.0
CB A:THR332 5.0 160.1 1.0
CA A:THR332 5.0 160.1 1.0

Reference:

R.Singh, A.Herrero Del Valle, J.D.Joiner, M.Zwaagstra, B.J.Ferguson, F.J.M.Van Kuppeveld, Y.Modis. Molecular Basis of Autoimmune Disease Protection By MDA5 Variants Biorxiv 2024.
ISSN: ISSN 2692-8205
DOI: 10.1101/2024.10.03.616466
Page generated: Sun Jul 6 22:41:44 2025

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