Aluminium in PDB 2ode: Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3

The structure of Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3, PDB code: 2ode was solved by C.Gileadi, M.Soundararajan, A.P.Turnbull, J.M.Elkins, E.Papagrigoriou, A.C.W.Pike, G.Bunkoczi, F.Gorrec, C.Umeano, F.Von Delft, J.Weigelt, A.Edwards, C.H.Arrowsmith, M.Sundstrom, D.A.Doyle, Structural Genomicsconsortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.40 / 1.90
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	112.837, 130.216, 68.519, 90.00, 90.00, 90.00
R / Rfree (%)	18 / 21.1

The structure of Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3 also contains other interesting chemical elements:

Fluorine	(F)	8 atoms
Magnesium	(Mg)	2 atoms

The binding sites of Aluminium atom in the Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3 (pdb code 2ode). This binding sites where shown within 5.0 Angstroms radius around Aluminium atom.
In total 2 binding sites of Aluminium where determined in the Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3, PDB code: 2ode:
Jump to Aluminium binding site number: 1; 2;

Aluminium binding site 1 out of 2 in the Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3


Mono view


Stereo pair view

A full contact list of Aluminium with other atoms in the Al binding site number 1 of Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Al2001 b:20.4 occ:1.00 AL A:ALF2001 0.0 20.4 1.0 F3 A:ALF2001 1.8 22.2 1.0 F4 A:ALF2001 1.8 21.4 1.0 F2 A:ALF2001 1.8 23.9 1.0 F1 A:ALF2001 1.8 22.5 1.0 O2B A:GDP1001 2.0 18.8 1.0 O A:HOH3236 2.1 18.5 1.0 PB A:GDP1001 3.3 19.4 1.0 MG A:MG3001 3.5 20.2 1.0 O1B A:GDP1001 3.7 22.3 1.0 NH1 A:ARG178 3.8 34.5 1.0 N A:GLU43 3.9 34.3 1.0 N A:THR181 3.9 32.4 1.0 NH2 A:ARG178 3.9 36.0 1.0 O A:HOH3231 3.9 19.9 1.0 O3B A:GDP1001 4.0 21.2 1.0 N A:GLY203 4.1 32.1 1.0 OE1 A:GLN204 4.1 32.5 1.0 NE2 A:GLN204 4.1 30.5 1.0 NZ A:LYS46 4.2 32.2 1.0 CA A:GLY42 4.3 33.8 1.0 CZ A:ARG178 4.3 36.6 1.0 O A:HOH3229 4.4 23.1 1.0 OG1 A:THR181 4.4 31.0 1.0 O3A A:GDP1001 4.4 20.1 1.0 CB A:THR181 4.4 33.6 1.0 O A:THR181 4.4 32.6 1.0 CD A:GLN204 4.6 29.9 1.0 CG A:LYS180 4.6 34.2 1.0 C A:GLY42 4.6 33.9 1.0 CE A:LYS46 4.6 31.7 1.0 CA A:THR181 4.7 33.0 1.0 CA A:GLY202 4.7 32.7 1.0 CA A:LYS180 4.7 33.0 1.0 CA A:GLU43 4.8 35.3 1.0 CA A:GLY203 4.8 32.1 1.0 C A:LYS180 4.9 32.7 1.0 C A:GLY202 4.9 32.5 1.0 O A:VAL201 4.9 32.8 1.0

Aluminium binding site 2 out of 2 in the Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3


Mono view


Stereo pair view

A full contact list of Aluminium with other atoms in the Al binding site number 2 of Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3 within 5.0Å range: probe atom residue distance (Å) B Occ C:Al2002 b:23.9 occ:1.00 AL C:ALF2002 0.0 23.9 1.0 F4 C:ALF2002 1.8 27.4 1.0 F1 C:ALF2002 1.8 24.6 1.0 F2 C:ALF2002 1.8 22.9 1.0 F3 C:ALF2002 1.8 22.0 1.0 O2B C:GDP1002 2.0 22.0 1.0 O C:HOH3194 2.1 18.7 1.0 PB C:GDP1002 3.2 21.2 1.0 MG C:MG3002 3.4 24.7 1.0 O1B C:GDP1002 3.6 19.8 1.0 NH1 C:ARG178 3.8 33.1 1.0 N C:GLU43 3.8 33.7 1.0 NH2 C:ARG178 4.0 32.0 1.0 O C:HOH3187 4.0 22.7 1.0 N C:THR181 4.0 30.3 1.0 O3B C:GDP1002 4.1 20.3 1.0 N C:GLY203 4.1 32.7 1.0 OE1 C:GLN204 4.1 33.0 1.0 NZ C:LYS46 4.1 32.0 1.0 NE2 C:GLN204 4.1 31.5 1.0 CA C:GLY42 4.2 34.0 1.0 O C:HOH3190 4.4 21.4 1.0 CZ C:ARG178 4.4 35.5 1.0 O C:THR181 4.4 32.2 1.0 O3A C:GDP1002 4.4 18.9 1.0 CB C:THR181 4.5 31.3 1.0 OG1 C:THR181 4.5 32.1 1.0 CD C:GLN204 4.5 30.6 1.0 C C:GLY42 4.6 34.5 1.0 CG C:LYS180 4.6 34.6 1.0 CA C:GLY202 4.6 32.2 1.0 CE C:LYS46 4.7 32.5 1.0 CA C:GLU43 4.7 34.4 0.5 CA C:GLU43 4.7 34.4 0.5 CA C:THR181 4.8 31.6 1.0 CA C:LYS180 4.8 30.8 1.0 CA C:GLY203 4.9 32.2 1.0 C C:GLY202 4.9 33.0 1.0 O C:VAL201 4.9 31.0 1.0 C C:LYS180 4.9 29.6 1.0

M.Soundararajan, F.S.Willard, A.J.Kimple, A.P.Turnbull, L.J.Ball, G.A.Schoch, C.Gileadi, O.Y.Fedorov, E.F.Dowler, V.A.Higman, S.Q.Hutsell, M.Sundstrom, D.A.Doyle, D.P.Siderovski. Structural Diversity in the Rgs Domain and Its Interaction with Heterotrimeric G Protein Alpha-Subunits. Proc.Natl.Acad.Sci.Usa V. 105 6457 2008.
ISSN: ISSN 0027-8424
PubMed: 18434541
DOI: 10.1073/PNAS.0801508105