Aluminium in PDB 4a36: Structure of Duck Rig-I Helicase Domain Bound to 19-Mer Dsrna and Atp Transition State Analogue

The structure of Structure of Duck Rig-I Helicase Domain Bound to 19-Mer Dsrna and Atp Transition State Analogue, PDB code: 4a36 was solved by E.Kowalinski, T.Lunardi, A.A.Mccarthy, S.Cusack, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.95 / 3.70
Space group	P 41
Cell size a, b, c (Å), α, β, γ (°)	129.270, 129.270, 106.310, 90.00, 90.00, 90.00
R / Rfree (%)	19.3 / 26.3

The structure of Structure of Duck Rig-I Helicase Domain Bound to 19-Mer Dsrna and Atp Transition State Analogue also contains other interesting chemical elements:

Fluorine	(F)	6 atoms
Magnesium	(Mg)	2 atoms

The binding sites of Aluminium atom in the Structure of Duck Rig-I Helicase Domain Bound to 19-Mer Dsrna and Atp Transition State Analogue (pdb code 4a36). This binding sites where shown within 5.0 Angstroms radius around Aluminium atom.
In total 2 binding sites of Aluminium where determined in the Structure of Duck Rig-I Helicase Domain Bound to 19-Mer Dsrna and Atp Transition State Analogue, PDB code: 4a36:
Jump to Aluminium binding site number: 1; 2;

Aluminium binding site 1 out of 2 in the Structure of Duck Rig-I Helicase Domain Bound to 19-Mer Dsrna and Atp Transition State Analogue


Mono view


Stereo pair view

A full contact list of Aluminium with other atoms in the Al binding site number 1 of Structure of Duck Rig-I Helicase Domain Bound to 19-Mer Dsrna and Atp Transition State Analogue within 5.0Å range: probe atom residue distance (Å) B Occ A:Al1796 b:34.3 occ:1.00 AL A:AF31796 0.0 34.3 1.0 F2 A:AF31796 1.8 35.8 1.0 F1 A:AF31796 1.8 35.2 1.0 F3 A:AF31796 1.8 39.5 1.0 O3B A:ADP1794 2.4 63.0 1.0 NZ A:LYS273 3.2 70.5 1.0 O2B A:ADP1794 3.2 66.5 1.0 PB A:ADP1794 3.3 68.7 1.0 NH2 A:ARG731 3.5 93.3 1.0 MG A:MG1795 3.5 35.9 1.0 OE2 A:GLU376 3.6 85.6 1.0 OE1 A:GLU376 3.6 83.0 1.0 CA A:GLY704 3.7 80.6 1.0 NH2 A:ARG733 3.7 81.1 1.0 OE1 A:GLN727 3.9 67.3 1.0 CD A:GLU376 4.0 82.2 1.0 N A:GLY704 4.0 83.3 1.0 NH1 A:ARG731 4.2 90.5 1.0 CE A:LYS273 4.2 72.2 1.0 CZ A:ARG731 4.3 92.3 1.0 OG1 A:THR269 4.3 0.1 1.0 C A:GLY704 4.4 81.4 1.0 O A:GLY704 4.4 80.0 1.0 O3A A:ADP1794 4.5 63.8 1.0 O1B A:ADP1794 4.5 66.1 1.0 N A:GLY270 4.7 82.0 1.0 CA A:THR269 4.8 79.5 1.0 CB A:THR269 4.9 85.6 1.0 CD A:GLN727 4.9 68.4 1.0 CZ A:ARG733 4.9 86.8 1.0

Aluminium binding site 2 out of 2 in the Structure of Duck Rig-I Helicase Domain Bound to 19-Mer Dsrna and Atp Transition State Analogue


Mono view


Stereo pair view

A full contact list of Aluminium with other atoms in the Al binding site number 2 of Structure of Duck Rig-I Helicase Domain Bound to 19-Mer Dsrna and Atp Transition State Analogue within 5.0Å range: probe atom residue distance (Å) B Occ B:Al1796 b:39.3 occ:1.00 AL B:AF31796 0.0 39.3 1.0 F2 B:AF31796 1.8 41.7 1.0 F1 B:AF31796 1.8 40.1 1.0 F3 B:AF31796 1.8 41.5 1.0 O3B B:ADP1794 2.3 60.6 1.0 O2B B:ADP1794 2.9 69.6 1.0 PB B:ADP1794 3.1 68.3 1.0 NZ B:LYS273 3.3 79.3 1.0 NH2 B:ARG731 3.4 71.6 1.0 NH2 B:ARG733 3.6 87.2 1.0 OE2 B:GLU376 3.7 75.5 1.0 OE1 B:GLU376 3.7 74.2 1.0 CA B:GLY704 3.8 73.4 1.0 MG B:MG1795 3.8 35.5 1.0 OE1 B:GLN727 3.9 73.5 1.0 NH1 B:ARG731 4.1 73.1 1.0 CD B:GLU376 4.1 76.1 1.0 N B:GLY704 4.1 78.9 1.0 O3A B:ADP1794 4.2 64.7 1.0 OG1 B:THR269 4.2 84.3 1.0 CZ B:ARG731 4.2 70.4 1.0 CE B:LYS273 4.3 73.9 1.0 O1B B:ADP1794 4.4 67.8 1.0 C B:GLY704 4.4 68.1 1.0 O B:GLY704 4.5 70.7 1.0 N B:GLY270 4.6 70.8 1.0 CA B:THR269 4.6 80.1 1.0 CB B:THR269 4.7 83.4 1.0 CZ B:ARG733 4.8 85.3 1.0 CD B:GLN727 4.9 72.4 1.0

E.Kowalinski, T.Lunardi, A.A.Mccarthy, J.Louber, J.Brunel, B.Grigorov, D.Gerlier, S.Cusack. Structural Basis For the Activation of Innate Immune Pattern Recognition Receptor Rig-I By Viral Rna. Cell(Cambridge,Mass.) V. 147 423 2011.
ISSN: ISSN 0092-8674
PubMed: 22000019
DOI: 10.1016/J.CELL.2011.09.039