Aluminium in PDB 5vhd: DHX36 with An N-Terminal Truncation Bound to Adp-ALF4

The structure of DHX36 with An N-Terminal Truncation Bound to Adp-ALF4, PDB code: 5vhd was solved by M.Chen, A.Ferre-D'amare, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.73 / 2.55
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	62.030, 112.500, 63.180, 90.00, 110.33, 90.00
R / Rfree (%)	17.3 / 21.3

The structure of DHX36 with An N-Terminal Truncation Bound to Adp-ALF4 also contains other interesting chemical elements:

Fluorine

(F)

4 atoms

The binding sites of Aluminium atom in the DHX36 with An N-Terminal Truncation Bound to Adp-ALF4 (pdb code 5vhd). This binding sites where shown within 5.0 Angstroms radius around Aluminium atom.
In total only one binding site of Aluminium was determined in the DHX36 with An N-Terminal Truncation Bound to Adp-ALF4, PDB code: 5vhd:

Aluminium binding site 1 out of 1 in the DHX36 with An N-Terminal Truncation Bound to Adp-ALF4


Mono view


Stereo pair view

A full contact list of Aluminium with other atoms in the Al binding site number 1 of DHX36 with An N-Terminal Truncation Bound to Adp-ALF4 within 5.0Å range: probe atom residue distance (Å) B Occ D:Al1102 b:90.6 occ:1.00 AL D:ALF1102 0.0 90.6 1.0 F4 D:ALF1102 1.8 85.0 1.0 F2 D:ALF1102 1.8 90.0 1.0 F3 D:ALF1102 1.8 88.7 1.0 F1 D:ALF1102 1.8 0.8 1.0 O3B D:ADP1101 2.4 84.3 1.0 NH2 D:ARG607 3.0 77.1 1.0 O D:HOH1211 3.2 57.7 1.0 NH2 D:ARG604 3.3 36.8 1.0 PB D:ADP1101 3.6 77.5 1.0 OE1 D:GLU337 3.9 63.6 1.0 O1B D:ADP1101 4.0 72.4 1.0 OE1 D:GLN600 4.0 41.2 1.0 N D:SER559 4.1 59.1 1.0 N D:GLY235 4.2 43.9 1.0 CZ D:ARG604 4.3 43.9 1.0 NH1 D:ARG604 4.3 41.5 1.0 CZ D:ARG607 4.3 67.7 1.0 O2B D:ADP1101 4.4 78.7 1.0 CA D:SER559 4.5 55.8 1.0 CA D:THR234 4.5 57.0 1.0 CB D:ALA369 4.6 53.3 1.0 CG2 D:THR234 4.6 55.7 1.0 CD D:GLU337 4.7 49.0 1.0 OE2 D:GLU337 4.7 42.2 1.0 O3A D:ADP1101 4.8 88.5 1.0 CB D:THR234 4.8 52.2 1.0 O2A D:ADP1101 4.9 85.8 1.0 C D:THR234 4.9 54.2 1.0 CD D:GLN600 4.9 43.3 1.0 NZ D:LYS238 4.9 79.0 1.0 NE2 D:GLN600 5.0 41.9 1.0 NH1 D:ARG607 5.0 69.3 1.0

M.C.Chen, R.Tippana, N.A.Demeshkina, P.Murat, S.Balasubramanian, S.Myong, A.R.Ferre-D'amare. Structural Basis of G-Quadruplex Unfolding By the Deah/Rha Helicase DHX36. Nature V. 558 465 2018.
ISSN: ESSN 1476-4687
PubMed: 29899445
DOI: 10.1038/S41586-018-0209-9