Aluminium in PDB 6xez: Structure of Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc

All present enzymatic activity of Structure of Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc:
2.7.7.48; 3.4.19.12; 3.4.22.69; 3.6.4.12; 3.6.4.13;

The structure of Structure of Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc also contains other interesting chemical elements:

Fluorine	(F)	6 atoms
Magnesium	(Mg)	3 atoms
Zinc	(Zn)	8 atoms

The binding sites of Aluminium atom in the Structure of Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc (pdb code 6xez). This binding sites where shown within 5.0 Angstroms radius around Aluminium atom.
In total 2 binding sites of Aluminium where determined in the Structure of Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc, PDB code: 6xez:
Jump to Aluminium binding site number: 1; 2;

Aluminium binding site 1 out of 2 in the Structure of Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc


Mono view


Stereo pair view

A full contact list of Aluminium with other atoms in the Al binding site number 1 of Structure of Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc within 5.0Å range: probe atom residue distance (Å) B Occ E:Al705 b:1.0 occ:1.00 AL E:AF3705 0.0 1.0 1.0 F3 E:AF3705 1.8 1.0 1.0 F2 E:AF3705 1.8 1.0 1.0 F1 E:AF3705 1.8 1.0 1.0 O2B E:ADP704 2.3 0.1 1.0 O1B E:ADP704 2.3 0.1 1.0 PB E:ADP704 2.5 0.1 1.0 O3B E:ADP704 2.7 0.1 1.0 O3A E:ADP704 4.1 0.1 1.0 CB E:LYS288 4.1 0.6 1.0 OE2 E:GLU375 4.3 0.9 1.0 MG E:MG706 4.3 0.9 1.0 NE2 E:GLN404 4.4 0.7 1.0 O E:PRO283 4.6 0.1 1.0 O E:GLY282 4.6 0.8 1.0 N E:GLY285 4.6 0.5 1.0 OG1 E:THR286 4.7 0.6 1.0 N E:THR286 4.9 0.6 1.0

Aluminium binding site 2 out of 2 in the Structure of Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc


Mono view


Stereo pair view

A full contact list of Aluminium with other atoms in the Al binding site number 2 of Structure of Sars-Cov-2 Replication-Transcription Complex Bound to NSP13 Helicase - NSP13(2)-Rtc within 5.0Å range: probe atom residue distance (Å) B Occ F:Al1004 b:0.4 occ:1.00 AL F:AF31004 0.0 0.4 1.0 F3 F:AF31004 1.8 0.4 1.0 F2 F:AF31004 1.8 0.4 1.0 F1 F:AF31004 1.8 0.4 1.0 O1B F:ADP1003 2.3 0.5 1.0 O2B F:ADP1003 2.3 0.5 1.0 PB F:ADP1003 2.5 0.5 1.0 O3B F:ADP1003 2.7 0.5 1.0 O F:GLY282 3.1 0.6 1.0 CB F:LYS288 3.7 0.3 1.0 C F:GLY282 4.1 0.6 1.0 O3A F:ADP1003 4.1 0.5 1.0 OG1 F:THR286 4.3 0.1 1.0 MG F:MG1005 4.3 0.0 1.0 OD2 F:ASP374 4.4 0.3 1.0 O F:PRO283 4.5 0.4 1.0 CA F:PRO284 4.5 0.0 1.0 C F:PRO283 4.5 0.4 1.0 N F:PRO284 4.6 0.0 1.0 CA F:GLY282 4.6 0.6 1.0 OD1 F:ASP374 4.8 0.3 1.0

J.Chen, B.Malone, E.Llewellyn, M.Grasso, P.M.M.Shelton, P.D.B.Olinares, K.Maruthi, E.T.Eng, H.Vatandaslar, B.T.Chait, T.M.Kapoor, S.A.Darst, E.A.Campbell. Structural Basis For Helicase-Polymerase Coupling in the Sars-Cov-2 Replication-Transcription Complex. Cell V. 182 1560 2020.
ISSN: ISSN 1097-4172
PubMed: 32783916
DOI: 10.1016/J.CELL.2020.07.033