Aluminium in PDB 8jpc: Cryo-Em Structure of NTSR1-GRK2-Galpha(Q) Complexes 2

All present enzymatic activity of Cryo-Em Structure of NTSR1-GRK2-Galpha(Q) Complexes 2:
2.7.11.15;

The structure of Cryo-Em Structure of NTSR1-GRK2-Galpha(Q) Complexes 2 also contains other interesting chemical elements:

Magnesium	(Mg)	1 atom
Fluorine	(F)	5 atoms

The binding sites of Aluminium atom in the Cryo-Em Structure of NTSR1-GRK2-Galpha(Q) Complexes 2 (pdb code 8jpc). This binding sites where shown within 5.0 Angstroms radius around Aluminium atom.
In total only one binding site of Aluminium was determined in the Cryo-Em Structure of NTSR1-GRK2-Galpha(Q) Complexes 2, PDB code: 8jpc:

Aluminium binding site 1 out of 1 in the Cryo-Em Structure of NTSR1-GRK2-Galpha(Q) Complexes 2


Mono view


Stereo pair view

A full contact list of Aluminium with other atoms in the Al binding site number 1 of Cryo-Em Structure of NTSR1-GRK2-Galpha(Q) Complexes 2 within 5.0Å range: probe atom residue distance (Å) B Occ Q:Al403 b:96.7 occ:1.00 AL Q:ALF403 0.0 96.7 1.0 F2 Q:ALF403 1.8 96.7 1.0 F3 Q:ALF403 1.8 96.7 1.0 F1 Q:ALF403 1.8 96.7 1.0 F4 Q:ALF403 1.8 96.7 1.0 O2B Q:GDP401 2.5 99.5 1.0 O3B Q:GDP401 3.4 99.5 1.0 PB Q:GDP401 3.5 99.5 1.0 MG Q:MG402 3.8 87.4 1.0 O2A Q:GDP401 3.9 99.5 1.0 N Q:GLU49 4.0 101.9 1.0 N Q:GLY208 4.1 88.3 1.0 N Q:THR186 4.1 89.8 1.0 NH2 Q:ARG183 4.2 103.4 1.0 CA Q:GLY48 4.3 92.4 1.0 O1B Q:GDP401 4.4 99.5 1.0 O Q:THR186 4.4 89.8 1.0 CA Q:PRO185 4.6 95.8 1.0 C Q:GLY48 4.7 92.4 1.0 NZ Q:LYS52 4.7 94.6 1.0 O3A Q:GDP401 4.7 99.5 1.0 CA Q:GLY207 4.8 80.2 1.0 NH1 Q:ARG183 4.8 103.4 1.0 CA Q:GLY208 4.8 88.3 1.0 CB Q:THR186 4.9 89.8 1.0 C Q:PRO185 4.9 95.8 1.0 CA Q:GLU49 4.9 101.9 1.0 CZ Q:ARG183 4.9 103.4 1.0 CA Q:THR186 4.9 89.8 1.0 C Q:GLY207 4.9 80.2 1.0 PA Q:GDP401 5.0 99.5 1.0

J.Duan, H.Liu, F.Zhao, Q.Yuan, Y.Ji, X.Cai, X.He, X.Li, J.Li, K.Wu, T.Gao, S.Zhu, S.Lin, M.W.Wang, X.Cheng, W.Yin, Y.Jiang, D.Yang, H.E.Xu. Gpcr Activation and GRK2 Assembly By A Biased Intracellular Agonist. Nature 2023.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-023-06395-9