Aluminium in PDB 8ox6: Cryo-Em Structure of ATP8B1-CDC50A in E1P Conformation

All present enzymatic activity of Cryo-Em Structure of ATP8B1-CDC50A in E1P Conformation:
7.6.2.1;

The structure of Cryo-Em Structure of ATP8B1-CDC50A in E1P Conformation also contains other interesting chemical elements:

Fluorine	(F)	4 atoms
Magnesium	(Mg)	1 atom

The binding sites of Aluminium atom in the Cryo-Em Structure of ATP8B1-CDC50A in E1P Conformation (pdb code 8ox6). This binding sites where shown within 5.0 Angstroms radius around Aluminium atom.
In total only one binding site of Aluminium was determined in the Cryo-Em Structure of ATP8B1-CDC50A in E1P Conformation, PDB code: 8ox6:

Aluminium binding site 1 out of 1 in the Cryo-Em Structure of ATP8B1-CDC50A in E1P Conformation


Mono view


Stereo pair view

A full contact list of Aluminium with other atoms in the Al binding site number 1 of Cryo-Em Structure of ATP8B1-CDC50A in E1P Conformation within 5.0Å range: probe atom residue distance (Å) B Occ A:Al1202 b:90.5 occ:1.00 AL A:ALF1202 0.0 90.5 1.0 F1 A:ALF1202 1.8 90.5 1.0 F4 A:ALF1202 1.8 90.5 1.0 F3 A:ALF1202 1.8 90.5 1.0 F2 A:ALF1202 1.8 90.5 1.0 OD1 A:ASP454 2.4 82.7 1.0 OD2 A:ASP454 2.6 82.7 1.0 CG A:ASP454 2.7 82.7 1.0 ND2 A:ASN896 2.8 84.0 1.0 OG1 A:THR732 3.1 92.1 1.0 NZ A:LYS873 3.6 86.1 1.0 MG A:MG1201 3.7 83.8 1.0 CG A:ASN896 4.0 84.0 1.0 CB A:ASP454 4.1 82.7 1.0 CB A:THR732 4.1 92.1 1.0 OE2 A:GLU914 4.3 84.2 1.0 OD1 A:ASP897 4.3 78.8 1.0 O A:THR456 4.4 85.3 1.0 OD1 A:ASN896 4.4 84.0 1.0 OD2 A:ASP897 4.5 78.8 1.0 CB A:THR456 4.5 85.3 1.0 N A:THR456 4.6 85.3 1.0 CE A:LYS873 4.7 86.1 1.0 CG A:ASP897 4.7 78.8 1.0 CA A:THR732 4.8 92.1 1.0 N A:LYS455 4.9 86.3 1.0 CA A:ASP454 5.0 82.7 1.0

T.Dieudonne, F.Kummerer, M.J.Laursen, C.Stock, R.K.Flygaard, S.Khalid, G.Lenoir, J.A.Lyons, K.Lindorff-Larsen, P.Nissen. Activation and Substrate Specificity of the Human P4-Atpase ATP8B1. Nat Commun V. 14 7492 2023.
ISSN: ESSN 2041-1723
PubMed: 37980352
DOI: 10.1038/S41467-023-42828-9